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Top 10 Drugstore Serums

10 Affordable Face Serums To Buy At The Drugstore

10 Affordable Face Serums To Buy At The Drugstore

Serums are one of those skincare products that everyone can use and benefit from, no matter their skin type. They’re different from moisturizers in that they are packed with highly concentrated active ingredients that can address a myriad of skin concerns—we're talking hyperpigmentation, wrinkles, dryness, the works. And even though serums are often associated with hefty price tags, we're proud to share 10 inexpensive face serums that will give you radiant and beautiful skin without the high price. That's right—we’ve searched the web using our data-driven algorithm to find the best face serums you can find in your local drugstore. Our data-driven algorithm factors in best-selling buzz, editorial selections, and real user reviews to create a vetted list of the best of the best. Ahead, find the Top 10 drugstore serums that won’t break your budget. Opening image: @lorealparis

Did you enjoy our 10 Best Drugstore Serums? Just wait till you see our 10 Best Vitamin C Serums!

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September 22, 2020

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Top 10 Lists serve as unbiased shopping guides to the most trusted product recommendations on the internet. Products are scored and ranked using an algorithm backed by data consumers find most valuable when making a purchase. We are reader-supported and may earn a commission when you shop through our links.

The Rankings

CeraVe Vitamin C Serum
Rank & Style Approved


CeraVe Vitamin C Serum

BEST FOR: Brightening and lightening dark spots

USERS SAID: "After about two weeks of use, this serum has greatly lightened and removed most of the redness on my neck. I use it twice a day. A little goes a long way!"

CeraVe Skin Renewing Retinol Serum

Overall Score



CeraVe Skin Renewing Retinol Serum


16376 User Reviews


Best Seller


Industry Recognition


Social Buzz

About Our Scoring System

In order for any product to be featured on Rank & Style, it must first meet the requirements set by our algorithm—a vetting process that allocates points based on consumer and industry data to score and rank products within a given category.

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Best Drugstore

Another candidate for best anti-wrinkle serum you can buy at a drugstore, CeraVe’s Skin Renewing Retinol Serum is both affordable and effective. In fact, it has all of the skincare heavy hitters in its dermatologist-developed formula: retinol, hyaluronic acid, niacinamide, and ceramides.

Because this product is free of fragrances and non-comedogenic, it’s safe for those who have skin sensitivities. However, retinol can increase your skin’s vulnerability to sun damage, so don’t skip the sunscreen if you plan on using this product.

Versed Just Breathe Clarifying Serum

BEST FOR: Clearing and detoxifying clogged pores

WHAT IT DOES: A combination of willow bark extract, zinc, and niacinamide help to remove dirt and debris from pores while reducing inflammation and irritation.

L'Oreal Revitalift Derm Intensives Pure Vitamin C Serum

LOVED FOR: This lightweight serum helps the skin look brighter and more radiant while neutralizing free radicals that can lead to early signs of aging.

HELPFUL TIP: After cleansing, apply this serum in the morning and follow with a moisturizer to avoid drying out the skin.

L'Oreal Revitalift Derm Intensives Hyaluronic Acid Serum

WHY YOU NEED IT: Hyaluronic acid is a savior for dry, lifeless skin. It can attract up to 1,000 times its weight in water and keeps moisture locked into the skin instead of seeping out. It’s the answer to all of your dry-skin woes.

USERS SAID: "If you have dry skin like I do, you need this serum! My face looks dewy and feels super hydrated. I've used other serums in the same price range, but I definitely like this one for moisture the most.”

RoC Retinol Correxion Deep Wrinkle Serum

LOVED FOR: A retinol formula that’s non-comedogenic, free of oils, and gentle enough for everyday use

HELPFUL TIP: Apply this serum on your face and neck for best results.

Neutrogena Rapid Wrinkle Repair Serum

BEST FOR: Reducing the appearance of wrinkles and fine lines

USERS SAID: "I am 50 years old and have forehead lines, which have been appearing over time. I like the way this serum has lessened the sight of those lines and made them less noticeable."

Olay Regenerist Regenerating Serum

WHY YOU NEED IT: This do-it-all serum that plumps, smooths, hydrates, and brightens is great for all skin types and concerns.

FROM THE EXPERTS: In a clinical study, 97% of women felt smoother skin after just two weeks.

Neutrogena Hydroboost Hydrating Serum

LOVED FOR: This oil-free serum balances moisture levels in the skin and keeps moisture locked in without leaving behind an icky, greasy feel.

USERS SAID: "My dermatologist suggested I stop paying premium prices for high-end skincare products and switch to the Neutrogena brand. He was right. This serum has taken care of my dry skin and balanced out the oily areas. It's not greasy at all."

The Ordinary Niacinamide 10% + Zinc 1%

Overall Score



The Ordinary Niacinamide 10% + Zinc 1%


28088 User Reviews


Best Seller


Industry Recognition


Social Buzz

About Our Scoring System

In order for any product to be featured on Rank & Style, it must first meet the requirements set by our algorithm—a vetting process that allocates points based on consumer and industry data to score and rank products within a given category.

Best Budget

This vitamin-packed blemish serum from The Ordinary has two main ingredients: niacinamide, a naturally-occuring supplement known to protect skin from environmental stressors, and zinc, a mineral commonly used in skincare for redness—more specially, for rosacea and acne.

If you’re looking for a product that’s vegan, cruelty-free, or formulated without alcohol, silicone, nuts, gluten, or fragrances, this is a good option for you.

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